"Whole blood transfusion reduces overall component transfusion in cases" by Jessian L. Munoz, Alison M. Kimura et al.
 

Title

Whole blood transfusion reduces overall component transfusion in cases of placenta accreta spectrum: a pilot program

Document Type

Article

Publication Title

The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians

Abstract

OBJECTIVE: Placenta accreta spectrum (PAS) is a group of placental invasion pathologies associated with significant morbidity to both mother and fetus. The majority of patients with PAS will require a blood transfusion at time of delivery and subsequent cesarean hysterectomy. The optimal approach to maternal acute blood loss resuscitation is currently unknown. METHODS: Here, we present a cohort analysis of 34 patients with pathology-confirmed PAS treated with either whole blood ( = 16) or component therapy ( = 18) for initial intraoperative resuscitation. RESULTS: We observed comparable results in post-operative outcomes with fewer overall transfusions and subsequently, lower volumes of resuscitation (=.03) with whole blood initial resuscitation. CONCLUSIONS: Whole blood transfusion may represent a viable option for initial resuscitation with lower resuscitation volumes and transfusion-associated complications without directly effecting post-operative outcomes in cases of PAS.

First Page

1

Last Page

6

DOI

10.1080/14767058.2021.1915275

Publication Date

4-26-2021

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