Title

Autoimmune Conditions: Systemic Lupus Erythematosus

Document Type

Article

Publication Title

FP essentials

Abstract

Systemic lupus erythematosus (SLE) is a complex autoimmune disease that can affect the musculoskeletal, integumentary, renal, neuropsychiatric, hematologic, cardiac, pulmonary, gastrointestinal, and reticuloendothelial systems. Most patients with suspected SLE are comanaged with a rheumatology subspecialist to confirm the diagnosis and assist in ongoing treatment. Management should focus on improving long-term outcomes, achieving remission, preventing tissue damage, and improving quality of life. Disease activity should be assessed at baseline and at follow-up visits using a validated instrument. Hydroxychloroquine is recommended for all patients with SLE and should be continued indefinitely unless contraindicated. Low-dose glucocorticoids can be used to manage most symptoms. When needed, immunosuppressive drugs and biologics can be used, depending on the affected body system.

First Page

18

Last Page

24

Publication Date

7-1-2020

This document is currently not available here.

Share

COinS