Transient biventricular apical ballooning: A unique presentation of the "broken heart"
Transient left ventricular (LV) apical ballooning and normal epicardial coronary arteries are the hallmarks of Takotsubo cardiomyopathy. The syndrome is often triggered by emotional or physiologic stress, and its pathogenesis is poorly understood. Current proposals focus on elevated cathecolamines in association with abnormal coronary artery endothelium, coronary microcirculation or LV geometry. Right ventricular (RV) involvement, as described in our patient, is not reported as a typical feature. Presence of RV dysfunction may affect the initial management of these patients and raises questions regarding the universal applicability of the currently proposed pathophysiologic mechanisms of this syndrome. © 2007 Wiley Periodicals, Inc.
Novak, Gregg; Kross, Kimberly; Follmer, Kristy; Brofferio, Alessandra; and Shirani, Jamshid, "Transient biventricular apical ballooning: A unique presentation of the "broken heart"" (2007). Department of Cardiovascular Medicine Articles & Publications. 54.