Percutaneous hepatic injection of rose bengal disodium (PV-10) in metastatic uveal melanoma
Journal of Clinical Oncology
PV-10 is a small molecule autolytic immunotherapy in clinical development for the treatment of solid tumors. When administered by intralesional injection, PV-10 can produce immunogenic cell death that may induce a T cell-mediated immune response against treatment refractory and immunologically told tumors. Adaptive immunity can be enhanced through combination with immune checkpoint blockade.
Patel, Sapna P.; Carter, Brett; Lu, Gary; Redstone, Ellen; and Wachter, Eric A., "Percutaneous hepatic injection of rose bengal disodium (PV-10) in metastatic uveal melanoma" (2020). Center for Medical Imaging & Interventional Radiology @SLUHN Articles & Publications. 1.