Impact of Hypertrophic Cardiomyopathy on In-Hospital Outcomes of Patients with Stress Cardiomyopathy

Document Type

Article

Abstract

Background

Stress cardiomyopathy with apical ballooning (SCAB) has been reported in patients with hypertrophic cardiomyopathy (HCM) as a unique pathophysiologic subset, particularly when associated with left ventricular outflow tract obstruction (LVOTO). We aimed to compare the baseline characteristics and hospital outcomes of patients with SCAB with or without HCM.

Methods

National Inpatient Sample database was queried using relevant ICD-10 codes to identify adults admitted with SCAB with preexisting HCM. Relevant ICD-10 codes were also used to define comorbidities and in-hospital outcomes.

Results

158,630 patients were admitted (2016 - 2019) with SCAB, of which 685 patients (0.8%) had HCM. Compared to patients without HCM, those with HCM were less often female (77% vs 83%), more often experienced syncope (6% vs 2%) and more often needed an implantable cardioverter-defibrillator placement (2% vs 0.5%). They had a higher incidence of ventricular arrhythmias (11% vs 6%), a lower comorbidity burden [i.e., Charlson comorbidity index > 3] (27% vs 43%), a lower length of hospital stay (5.4 vs 6.8 days) and none of them developed cardiogenic shock or died during hospitalization (0% vs 6%). Surgical myectomy was performed in 21 (3%) of HCM patients. Rescue alcohol septal ablation was not reported during our study period.

Conclusion

Patients admitted with SCAB and HCM experience more ventricular arrhythmias but have good overall in-hospital outcomes with no reported mortality during this study period.

First Page

465

DOI

10.1016/S0735-1097(23)00909-9

Publication Date

3-7-2023

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