Baseline Characteristics and Outcomes of Marfan Patients with Atrial Fibrillation: Insights from the National Inpatient Sample
Document Type
Article
Abstract
Background: Marfan Syndrome (MFS) patients are at an increased risk for atrial arrhythmias. Among MFS patients who develop atrial fibrillation (AF), limited data exists on hospital outcomes and characteristics.
Methods: National Inpatient Sample 2018-2019 was used to identify patients with primary diagnosis of AF with and without a concurrent diagnosis of MFS using appropriate ICD-10 codes. Logistic regression was used to compare characteristics and in-hospital outcomes.
Results: 5,641,455 patients with AF were evaluated between 2018-2019 of which 2055 (0.04%) had a concurrent diagnosis of MFS. AF without MFS were older (75.28 ± 0.07-vs. 58.43 ± 1.6) and mainly carried the diagnosis of paroxysmal AF (64.94%). MFS patients with AF had higher rates of ICU admission (10.95%-vs-5.90%, p=0.020), cardiogenic shock (3.89-vs-1.96%, p=0.031), and ICD presence (9.25%vs-5.09%, p<0.001). Additionally, these patients underwent AF ablation more often (3.89%-vs.-1.47%, p<0.001).
Conclusion: Despite non-MFS AF patients being older, worsened clinical outcomes were seen in MFS with AF patients. Additionally, most comorbidities, LOS, and type of AF were relatively the same between groups. Further studies are needed to determine how AF may disproportionately affect MFS patients’ clinical outcomes.
First Page
113
DOI
10.1016/S0735-1097(24)02103-X
Publication Date
4-2024
Recommended Citation
Roma N, Desai S, Pattoli M, Krinock M, Ferraro JR BF, Alhudairy M, Plamenac J. BASELINE CHARACTERISTICS AND OUTCOMES OF MARFAN PATIENTS WITH ATRIAL FIBRILLATION: INSIGHT FROM THE NATIONAL INPATIENT SAMPLE. Journal of the American College of Cardiology. 2024 Apr 2;83(13_Supplement):113-.