Behcet's Disease Presenting as Pancolonic Ulcerations in a Patient With Kikuchi-Fujimoto Disease: A Rare Gastrointestinal Manifestation

Authors

Frank Lin, Internal Medicine, St. Luke's University Health Network, Bethlehem, PA
Ayah Obeid, Internal Medicine, St. Luke's University Health Network, Bethlehem, PA
Harsh Bhalala, Internal Medicine, St. Luke's University Health Network, Bethlehem, PA
Nishit Patel, Internal Medicine, St. Luke's University Health Network, Bethlehem, PA
Li Ge, Internal Medicine, St. Luke's University Health Network, Bethlehem, PA
Ronak Modi, Internal Medicine, St. Luke's University Health Network, Bethlehem, PA

Document Type

Article

Abstract

Kikuchi-Fujimoto disease (KFD) is a rare and self-limiting disorder characterized by cervical lymphadenopathy and fever. In this report, we present a case of a 24-year-old man with known history of KFD who presented with lower gastrointestinal bleeding and acute blood loss anemia. Further evaluation with colonoscopy showed widespread ulcerations in the colon and terminal ileum with suspicion for Behcet's disease. Biopsy from the colonic mucosa and ileocecal valve demonstrated focal ulcer with cryptitis and lymphoid aggregates that can be seen in Behcet's syndrome; however, it lacks specificity and Behcet's disease is a clinical diagnosis. This case emphasizes the importance of including gastrointestinal bleeding as a potential manifestation due to Behcet's disease in patients diagnosed with KFD.

First Page

e01455

DOI

10.14309/crj.0000000000001455

Publication Date

9-1-2024

Recommended Citation

Lin F, Obeid A, Bhalala H, Patel N, Ge L, Modi R. Behcet's Disease Presenting as Pancolonic Ulcerations in a Patient With Kikuchi-Fujimoto Disease: A Rare Gastrointestinal Manifestation. ACG Case Reports Journal. 2024 Sep 1;11(9):e01455.